KAJIAN INTERAKSI OBAT PADA PASIEN KANKER LEHER RAHIM (Serviks Uteri) RAWAT INAP DI RSUP Dr. KARYADI SEMARANG TAHUN 2007
ABSTRACT: Cervical uterine
cancer is a deadly tumor attacking the cervix uteri. In Indonesia, cervix uteri
cancer constitutes the most aggresive and deadly cancer. Frequently,
combinations of several different drugs are used for treating this disease. The
purpose of this study was to find out the stastisticts and kind of drug
interactions hospitalized in Dr. Kariadi Hospital Semarang for cervix uteri
cancer in 2007. This study was a non-experimental research conducted
retrospectively. The research was implemented to the medical records for cervix
uteri cancer patients hospitalized in Dr. Kariadi Hospital Semarang. Data
obtained were analysed with descriptive non-analytic method. The result of this
study showed that 96 in-patients of cervix uteri cancer, 55 patients (57,29 %)
had drug interactions, while 41 patients (42,7 %) had not drug interactions.
From a total number of 149 cases, 134 cases (89,93 %) had drug interaction,
while 15 cases (10,07 %) had not drug interaction. Based on the types of
interactions, 6 patients (4,48%) had pharmakokinetic interactions and the other
128 patients (95,52 %) had unknown mechanism drug interactions. The most drugs
producing interactions were midazolam and propofol.
Key words: Drug Interactions,
Cervix Uteri Cancer, Cer, Dr. Kariadi Hospital
Penulis: Ibrahim arifin, Nurul
latifah, Mustofa
Kode Jurnal: jpfarmasidd080028
