PENGARUH PERBEDAAN KONSENTRASI EKSTRAK ETER REBUSAN DAUN SIRIH (Piper betle Linn) DALAM SEDIAAN SALEP TERHADAP SIFAT FISIK DAN DAYA ANTIBAKTERINYA
ABSTRACT: Betle leaves has
been used as antibacteria or antiseptic and was formulated in gargle. Betel
leaves extract formulated in ointment in order to practical and effective to
the skin. The aim of this research is to know the influence of difference
concentration of betle leaves extract in ointment to its physical properties
and antibacteria effet against Staphylococcus aureus. Extract was obtained from
leaves of the plant by decoction and continued by extraction with ether.
Ointment were made in fine formulas with extract concentration 0.2, 0.4, 0.6,
0.8 and 1% w/w. The ointment was tested for its physical properties such as
consisted of homogenity, viscosity, stickness and spreadibility. Antibacterial
activity againts Staphylococcus aureus was tested by diffusion method. The
result of this research shown that the ointment homogenous. The difference of
extract concentration had not influence on their viscosity and dispersive
power, however had influence on their fixed time. The ointment of betle leaves
extract had antibacterial activity againts Staphylococcus aureus.
Keywords: Betle leaves extract, Ointment, Physical Test, antibacteri
Penulis: Yulias ninik
windriyati, Esti oktaria
Kode Jurnal: jpfarmasidd080031
