PENGARUH VARIASI KONSENTRASI EKSTRAK ETANOLIK DAUN TEH HIJAU (Camelia sinensis L.) DALAM SEDIAAN KRIM TERHADAP SIFAT FISIK DAN AKTIVITAS ANTIBAKTERI
ABSTRACT: Green tea is one of
a herbal nature which has been proved its special virtue anti acne. Green tea
leaf contains of 30-40% polifenol which is known as katekin has a
characteristic as antimicroba.To make it easier to use, the extrac etanolic of
green tea leaf is made in cream formulation. The purpose of this experiment is
to know variation concentration effect of green tea etanolic extract in cream
formulation to the physic and antibacteria activity especially for the acne
bacteria, also in spesific concentration will be find the best of extrac
etanolic green tea leaf toward physic characteristic and anti bacterial
activity. In this experiment, the thick extrac of green tea leaf is obtained by
maseration way of the using 50% etanol liquid. The cream is made in five
formulas that is using the extrac etanolic of green tea leaf for 1%, 3%, 5%, 7%
and 9% concentration with the modification formula of anti acne cream. Cream is
tested the physical characteristic including the homogenity , isolation
percent, spreading, and adhesing and also for antibacterial activity. The data
is analysed by non parametric statistical using Kruskal Wallis test continued
by doing Mann Whitney test with 95% of trust capacity. The result in this
experiment showes that the cream of extrac etanolic form of green tea leaf in
any cream concentration have good homogenity and did not isolation. As biger
concentration of cream extrac etanolik of green tea leaf as a smaller spreading
test and adhesing test but as a biger antibacterial activity toward
Staphylococcus aureus bacterial. Cream extrac etanolik of green tea leaf as a
control positive in physic characteristic and antibacterial activity is 7%
concentration.
Key words: Green tea of
extract etanolic, Cream, Physic characteristic test, Bacterial activity test
Penulis: Nanik widyaningrum, Mimik
murrukmihadi, Syarifatun karuniaekawati
Kode Jurnal: jpfarmasidd090018