ABSTRACT: Red fruit (Pandanus
conoideous Lam.) has been known by public as a medicine for any kind of
diseases, among of them is for cancer. To determine the carcinogenesis inhibition
effect of red fruit extract , we have examined the effect on
7,12-dimethylbenz[a]anthrasene (DMBA)-induced rat lungs cancer model in female Sprague-Dawley
rats. The extract was tested at 0.21 ml/200 g bw; 0.43 ml/200 g bw and 0.88 ml/
200 g bw. The experiment was terminated at day 120. Lung histology was used to
evaluate carcinogenesis inhibition. The result showed that the extract at 0.21
ml/200g bw improved lung carcinogenesis inhibition than other dose.
Key words: red fruit extract,
DMBA, lung cancer, Pandanus conoideus
Penulis: Abdul Mun‘im,
Retnosari Andrajati, Heni Susilowati
Kode Jurnal: jpfarmasidd060002
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