Hubungan serum seng dengan jumlah CD4 pada lansia di Panti Jompo
ABSTRACT: Elderly
people tend to
have higher susceptibility to
infections because of
immune dysfunction, especially
cell-mediated immune system which is related to zinc deficiency. Zinc has an
important role in the cellmediated immune system which can be determined by CD4
count.
Objectives: To determine the zinc level in the serum and CD4 count in
healthy elderly and the correlation between the zinc level in the serum and CD4
count.
Method: This was a randomized
cross-sectional study. Twenty seven
healthy elderly subjects of both sexes aged 60-90 years
were recruited for
this study from
a senior center.
Zinc level in
the serum and
CD4 count were measured.
Result: The average of CD4 count was 710 + 269 cells/ml, and the average of zinc level
in the serum was 87,29 + 10,27 μg/dL. Twenty six percent elderly had low CD4
count (<460cells/ml. There was no zinc deficiency among the elderly but 30%
elderly had zinc level 70- 80 μg/dL. There was a significant correlation
(p<0,05) between zinc level and CD4 count, which was analyzed using Pearson
correlation method.
Keywords: Zinc level, CD4 count, elderly
Penulis: Maria Widijanti
Sugeng, Merryana Adriani, Bambang Wirjatmadi
Kode Jurnal: jpkesmasdd130252
