Antiproliferatif Ekstrak Metanol Daun Dianella nemorosa Lam. (Liliaceae) terhadap Sel Kanker MKN45 dengan Menggunakan Metode WST-1
Abstract: Dianella nemorosa
Lam. was known containing alkaloids, terpenoid, phenolic compouds and tanin.
Antiproliferative effect of D. nemorosa leaves methanol exctract, which
demonstrated to have an in vitro cytotoxic effect on cancer cell line. The aim
of research was examined the effect antiproliferative methanol extract of D.
nemorosa leaves against MKN45 (gastric cancer) cell line. Leaves powder
extracted using methanol. Antiproliferative effect was determined by Cell
Proliferation Reagents WST-1
((2-(4-iodophenyl)-3-(4-nitro-phenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium
monosodium salt). Test for 1h, 2h, and 4h after incubated for 72h was done. The
result of this research showed that methanol exctract from D. nemorosa
possessed remarkable no had antiproliferative activity against MKN45 cell line.
The result indicated methanol extract of D. nemorosa leaves selective
inhibitory effect or antiproliferative against cell line.
Penulis: Aditya Krishar Karim,
Sismindari Sismindari
Kode Jurnal: jpbiologidd110092
