Status Gizi dan Status Besi Anak Kontak Tuberkulosis Serta Perannya dalam Kejadian Infeksi dan Sakit
Abstract: Indonesia is one of
the countries with the largest tuberculosis (TB) cases in the world. In endemic
area, TB in children account for 12–20% from all TB cases. Children living with
active TB adult cases are at higher risk for infection and disease development.
This research aimed to explore nutritional and iron status on children living
with active adult TB case in assosiation with infected and disease development.
In a cross-sectional study design, children living with active TB adult for at
least 8 weeks were recruited. Clinical examination, TST, and chest X ray were
performed on these children, along with blood examination for complete blood
analyses and iron status. For nutrition status, weight, height and age were
calculated using CDC standard calculation. Ferritin, serum iron TIBC were
measured for iron status. Mycobacterial 16S rRNA in cell was studied in 43 sub
sample. Faeces was collected to explore helminthes infection. Home visit was
done three times randomly for each child to observed nutrition intake. Of 56
index cases with active TB adult who lived in a low socio economic condition,
73 contact TB children were recruited. These children were classified as sick
when they showed clinical signs (42.4%), indicating they had TB disease, or
otherwise classified as not sick (57.6%). Surprisingly, all mycobacterial 16S
rRNA examination in a subset randomized of 43 samples showed positive results,
suggesting that all contact TB children were infected with M.tuberculosis.
Nutritional status was generally poor, however, the iron status was within
normal range. Anemia in these children was only found in 2 of 73 (2.7%). Of 50
sub sample examined, no helminthes infection was found. Only Weight per age had
significant different between sick and not sick. Hemoglobin, feritin, iron
serum, TIBC and transferin saturation were in a normal range value, and its no
significant different found. The sick group had higher feritin, but lower on
elses but its not exceded significant level.
Penulis: Pudji Lestari, Anang
Endaryanto, Edhyana Sahiratmadja, Suharto
Kode Jurnal: jpbiologidd110051
