Aktivitas Antioksidan dan Penghambat Xantin Oksidase dari Ekstrak Buah Andaliman (Zanthoxylum acanthopodium DC.)
Abstract: The fruits of
andaliman (Zanthoxylum acanthopodium DC.) are well known in North Sumatera and
commonly used as seasoning for Batak traditional cuisine. Aims of this study
were to determine the scavenging activity of free radicals and xanthine oxidase
inhibitory activity from the andaliman fruit extracts after macerated garually
in petroleum ether, dichloromethane, ethyl acetate, n-butanol, and methanol.
Activity assay were evaluated in vitro by using DPPH and enzyme xanthine
oxidase. The result showed that n-butanol extract has medium antioxidant
activity with IC50 values of 53.51 μg/mL and methanol extract has strong antioxidant
activity with IC50 values of 26.39 mg/mL. Xanthine oxidase inhibitory activity
of the extract given by n-butanol and methanol are very strong with IC50 values
of 3.69 μg/mL and 4.03 μg/mL.
Penulis: Ruth Elenora
Kristanty, Abdul Mun'im, Katrin
Kode Jurnal: jpfarmasidd130027
