Hubungan Antara Pajanan Pestisida dengan Kejadian Dislipidemi pada Wanita Usia Subur (WUS) di Desa Gombong Kecamatan Belik Kabupaten Pemalang
Abstract: One of the impact of
pesticide exposure to women of childbearing age is dislipidemia. Dislipidemiaon
women can cause reproductive disorder such as infertility, spontaneous
abostion, fetal growth disordere andpremature birth. This research aimed is to
prove that pesticide exposure is the risk factor for dislipidemi on WCA.Method:
It was a cross-sectional study on 38 subjects Pesticide exposure was measured
by asking WCA’s involvementin agricultural activities using structured
questionnaire and by checking their level of cholinesterase. Incidenceof
dislipidemi measured using blood lipid profile parameters (total cholesterol,
HDL, LDL and triglycerides).Confounding variables included in this research
were age, level of education, nutritional status, hormonalparticipation KB,
cigarette smoke exposure history.Result: The prevalence of dislipidemi on WCA
was 44.7%. Subjects with cholinesterase levels below the averagewere 20 people
(52.6%) with a mean ± SD was 8.9395+1.37556. Pesticide exposure is a risk
factor dislipidemi (p= 0.024, 95% CI = 1.167 to 6.094).Conclusion: The higher
the degree of exposure to pesticides, the greater the risk of dislipidemia.
Based on dataand theory study, the pathogenesis of dislipidemi allegedly
through the barriers of lipase function, thyroid hormoneresistance and the
accumulation of pollutants in fatty tissue.
Penulis: Slamet Budiono,
Suhartono, Nurjazuli
Kode Jurnal: jpkesmasdd130459