EOSINOPHILIA IN PHYSICAL EXERCISE STRESSOR: PATHOBIOLOGY OR PHYSIOBIOLOGY?
ABSTRACT: Eosinophilia plays
an important role in asthmatic airway inflammation or allergy. Exercise dose
that can increase eosinophil in blood remains controversial. Blood eosinophil
measurement was carried out in males of 17 - 22 years old who performed several
intensive physical exercises. They were
divided into the following groups: Group I, physical exercise program group,
comprising high school students who involved in a physical exercise study on
the effect of 80-90% maximum heart rate on immunity; Group II, the athletes
of Pekan Olahraga Nasional XVI 2004 in
East Java; Group III, football athletes prepared for National Football League,
and control data were taken from students who did not perform intensive
exercise. The results of blood eosinophil measurement were as follows: 0.3158 ±
0.3238; 0.3475 ± 0.2285; 0.4305 ± 0.3146; 0.2760 ± 0.1873 (x10e3 /uL). More
strenuous physical exercise was found to increase blood eosinophil, although
not significant (ANOVA, p > 0.05). The eosinophilia itself may either
aggravate allergic disease or even as a reflection of immunity status
improvement, a possibility that worth to be investigated further.
Author: Sunarko Setyawan
Journal Code: jpkedokterangg050046