EOSINOPHILIA IN PHYSICAL EXERCISE STRESSOR: PATHOBIOLOGY OR PHYSIOBIOLOGY?

ABSTRACT: Eosinophilia plays an important role in asthmatic airway inflammation or allergy. Exercise dose that can increase eosinophil in blood remains controversial. Blood eosinophil measurement was carried out in males of 17 - 22 years old who performed several intensive physical exercises. They  were divided into the following groups: Group I, physical exercise program group, comprising high school students who involved in a physical exercise study on the effect of 80-90% maximum heart rate on immunity; Group II, the athletes of  Pekan Olahraga Nasional XVI 2004 in East Java; Group III, football athletes prepared for National Football League, and control data were taken from students who did not perform intensive exercise. The results of blood eosinophil measurement were as follows: 0.3158 ± 0.3238; 0.3475 ± 0.2285; 0.4305 ± 0.3146; 0.2760 ± 0.1873 (x10e3 /uL). More strenuous physical exercise was found to increase blood eosinophil, although not significant (ANOVA, p > 0.05). The eosinophilia itself may either aggravate allergic disease or even as a reflection of immunity status improvement, a possibility that worth to be investigated further.
Keywords:  eosinophilia, physical exercise program
Author: Sunarko Setyawan
Journal Code: jpkedokterangg050046

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