Skrining Fitokimia dan Uji Aktivitas Sitotoksik dari Tumbuhan Sarang Semut (Myrmecodia beccarii Hook.f.) Asal Kabupaten Merauke

ABSTRACT: Sarang semut (Myrmecodia beccarii Hook.f.) is a famous medicinal plant of Papua, which has traditionally potential in  treating  a  wide  variety  of  mild  and  severe  illnesses,  such  as  cancers  and  tumors,  gout,  coronary  heart  disease, hemorrhoids,  tuberculosis,  migraines,  rheumatism,  and  leukemia.  The  purposes  of  this  study  were  to  determine the content of the active compound group and the cytotoxic activity of sarang semut plants from Merauke Region. The  extraction  was  done  by  maceration  using  96  %  ethanol.  The  concentration  of  ethanolic  extract  were  0, 25, 50, 75,  100  ppm.  The  results  of  the  study  showed  that  the  cytotoxic  activity  determine  using  BSLT  (Brine  Shrimp Lethality  Test)  method  have  a  high  cytotoxic  activity  with  LC50  values  of  22.86  ppm  and  containing  the  active compound namely flavonoids, tannins and saponins separately. The ethanolic extract of tuber of sarang semut (M. beccarii) has a high cytotoxic activity against larvae of Artemia salina Leach according BSLT method.
Key words: Active compound, M. beccarii, cytotoxic activity, Merauke
Penulis: MODUSTRIARTI P. MARDANY, LINUS Y. CHRYSTOMO, ADITYA K. KARIM
Kode Jurnal: jpbiologidd160003

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