UJI EKSTRAK ETANOL DAUN PEGAGAN (CENTELLA ASIATICA L. URBAN) TERHADAP FERTILITAS TIKUS PUTIH (RATTUS NORVEGICUS L.) BETINA PADA TAHAP PRAIMPLANTASI
ABSTRACT: This study aims to
test extract ethanol of leaves Pennywort (Centellaasiatica L. Urban) toward
fertilitation of female white mice Sprague Dawley strain at the
praimplantation. Parameters used implantation (IM), loss of gestation (KGE) and
death of pasca-implantation (KPI) after 15 days pregnant.This research
conducted from April 2014 in the biology laboratory of UHAMKA, East Jakarta.
The sample used 24 rat that divided into four treatment, namely: control(D0),
125(D1), 150(D2 and 175 mgkg-1 bw(D3)with Complete Random Design.The results of
data by paired samples test analysis obtained significant differences
(p<0,05) between the control group ( D0 ) with the doses 150 mgkg-1 bb (D2)
on the decline IM and an increase KGE.On the percentage the average KPI
obtained influence is no real different ( p>0.05 ) in all treatment, but a
tendency increased the KPI average percentage in the doses 175 mgkg-1 bw
(D3).The conclution of this researchis the ethanol extract of leaves Pennywort
can reduce the percentage of the average number on implantation (IM) and
increase the loss of gestation (KGE) with an effective dose of 150 mgkg-1 bw.
Then, the tendency to raise the post-death implantation (KPI) early stage at a
dose of 175 mgkg-1 bw.
Penulis: Yassir Dzulfiqor,
Budhi Akbar, Susilo
Kode Jurnal: jpbiologidd150721
