UJI FITOKIMIA, TOKSISITAS DAN AKTIVITAS ANTIBAKTERI dari EKSTRAK BERBAGAI FRAKSI DAUN MAHANG (Macarang apruinosa (Miq.) Mull. Arg.) terhadap BAKTERI Escherichia coli dan Staphylococcus aureus
Abstrak: Phytochemical,
toxicity and antibacterial activity tests of total extract, fractions of
n-heksana, ethyl acetate and ethanol-water from mahang leaf (Macaranga pruinosa
(M.) M. A.) from KRUS (Kebun Raya Unmul Samarinda), East Kalimantan has been
carried out. Based on the secondary metabolites phytochemical test of the
(Macaranga pruinosa (M.) M. A.) leaf show that total extract is contain
alkaloid and steroid. n-hexane fraction is contain alkaloid and steroid. Ethyl
acetate fraction is contain steroid. Ethanol-water fraction is contain alkaloid
and phenolic. Brine shrimp lethality test values obtained Lethal Concentration
50 % (LC50) total extract 27,5036 ppm , n-heksana fraction 12,0773 ppm, ethyl
acetate fraction 23719,2305 ppm and ethanol-water fraction 250,0384 ppm.
Antibacteria activity test of extracts for Staphylococcus aureus bacteria
(positive Gram) and Escherichia coli (negative Gram) minimum inhibitor consentration
of 0-1 % (b/v) from extract fractions of n-heksana and fractions ethyl acetate
for Staphylococcus aureus bacteria and fractions ethyl acetate for Escherichia
coli bacteria.
Penulis: Mustafidah, Chairul
Saleh, Alimuddin
Kode Jurnal: jpkimiadd140683
