UJI PRAKLINIK ANTIHIPERURISEMIA SECARA IN VIVO PADA MENCIT PUTIH JANTAN GALUR BALB-C DARI EKSTRAK DAUN SALAM (Syzigium polyanthum Walp) DAN DAUN BELIMBING WULUH (Averrhoa bilimbi L.)
Abstract: Antihyperuricemia
activity in vivo testing has been done of single and combined extracts of Salam
(Syzigium polyanthum Walp) and Belimbing Wuluh leaves (Averrhoa bilimbi L.),
and also standardized extracts. Salam leaves extraction and Belimbing Wuluh
leaves carried by the water solvent. Dried extract of each ingredient had been
done antihyperuricemia preclinical in vivo testing against male white mice
strain Balb-C induced by potassium oxonate dose of 250 mg / kg b.w.
Antihyperuricemia preclinical in vivo testing results showed that the single
extracts of Salam and Belimbing Wuluh at a dose of 200 mg / kg b.w. had lower
activity levels of uric acid in the blood serum of male white mice,
respectively 0.640 and 0.680. While the activity of the combination of extracts
of Salam-Belimbing Wuluh is 1.380.
Keywords: Antihyperurisemia
preclinical in vivo testing; Salam leaves extract, Belimbing Wuluh leaves
extract, male white mice Balb-C
Penulis: Muhtadi, Andi
Suhendi, Nurcahyanti Wahyuningtyas, EM. Sutrisna
Kode Jurnal: jpkedokterandd140568
