ANTI-OXIDANT AND ANTI-DIABETIC ACTIVITIES OF ETHANOLIC EXTRACT OF Primula denticulata FLOWERS
Abstract: The present
investigation was carried out to focus on the anti-oxidant and anti-diabetic
effect of ethanolic extract of flowers of
Primula denticulata by DPPH, ferrous chelating, reducing power assay and
streptozotocin induced diabetes respectively. Dose selection was made on the
basis of acute oral toxicity study (100mg/kg, 200mg/kg, 400mg/kg bodyweight) as
per OECD guidelines 423. The blood
glucose levels were measured by using blood glucose measuring strips based on
glucose-oxidase method. The extract showed significant anti-oxidant and
anti-diabetic activity when compared with standard drug.
Author: Hemlata Bhatt, Sarla
Saklani, Kumud Upadhayay
Journal Code: jpfarmasigg160026
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