Efek Diuretik dan Daya Larut Batu Ginjal Dari Ekstrak Daun Mangkokan (Nothopanax scutellarium. Merr)
Abstract: Research on the
effects of diuretics and solubility of kidney stones of Mangkokan leaf
(Nothopanax scutellarium Merr.) extract has been done. Testing the solubility
of kidney stones performed on 4 groups of test animals, namely the control
group (without extract), The treatment dose groups of 0.5%, 1%, and 2%. Level
of kidney stones are dissolved in the control group, 0.5%, 1% and 2% are
0.00521%, 0.01232%, 0.02433% and 0.05669% respectively. These result indicate a
difference in dissolving kidney stones. Diuretic effect tested on 15 white male
rats were divided into 5 groups of tests, one positive control group
(furosemide), 1 negative control group (tween 80 1%), 3 treatment groups (doses
of 125; 250 and 500 mg/kg BW). The result showed that all of three doses of
extract have diuretic effect.
Penulis: Elisma, Fitri Maya
Sari, Helmi Arifin
Kode Jurnal: jpfarmasidd100084
