EFEK PEMBERIAN JUS BUAH PISANG KEPOK (Musa paradisiaca forma typica) TERHADAP KADAR GLUKOSA DARAH TIKUS JANTAN GALUR WISTAR YANG TERBEBANI GLUKOSA
Abstract: This research aimed
to determine the effects of administration of Musa paradisiaca forma typica
juice on blood glucose levels and determine what dose of Musa paradisiaca forma
typica juice which is most effective for lowering blood glucose levels in rats
burdened glucose. This research was experimental with study with one way
complete design using 25 male rats were divided into five groups. Group I
(negative control) was given CMC 1%, group II (positive control) was given
Glibenclamide dose of 0,64 mg/kgBW and group III, IV, V the rats were given 5;
10; 20 mL/kgBW dose of Musa paradisiaca forma typica juice, all of the
processes were given through the oral method. Hypoglycemic effect of Musa
paradisiaca forma typica juice was tested by following the Oral Glucose
Tolerance Test (OGTT) method. The blood-glucose contents were taken, at the 0
minutes before the OGTT and also taken at minutes of 15, 30, 60, 90, 120, 180,
and 240 after the OGTT, from the tested animal that had been gotten the
pre-treatment of the negative control, positive control and Musa paradisiaca
forma typica juice before. Data of blood glucose levels was statistically
analyzed using one way ANOVA and Scheffe test with 95% convidence level. The
result of this research showed that Musa paradisiaca forma typica juice can
lowering blood glucose levels on rats in burdened glucose. Dose Musa
paradisiaca forma typica juice are most effective in lowering blood glucose
levels in a dose was 10 mL/kgBW.
Penulis: F. Eki Supra Bawati,
Yunita Linawati
Kode Jurnal: jpfarmasidd130311
