SUATU KAJIAN MOLEKULER KETERGANTUNGAN NIKOTIN
Abstract: Nicotine, a simple
chemical substance from tobacco, stimulates addiction by neuroadaptation
inducing rewards system in human brain. Molecular mechanism of nicotine
addiction in rewards system are mediated by nicotinic acetylcholine receptor
(nAChR) and activate dopaminergic neuron. Thus, nicotine addiction are also
induce other neurottransmitter and hormone release: norephinefrin, serotonin,
opioid, glutamat and mono amine oxidase.
Penulis: Agustina Setiawati
Kode Jurnal: jpfarmasidd130315
