AKTIVITAS ANTIBAKTERI JAMU MADURA SUBUR KANDUNGAN
Abstract: Madurese traditional
medicine (herbs) Subur Kandungan is a medicine that is widely used and produced
in Madura that contains Curcuma zedoaria (Chrism.)Rosc., Kaempferia galanga L.,
Foeniculum vulgare Mill., and Centella asiatica (L.)Urb. highly favoredby the
Indonesian community, especially women to improve reproductive health but have
not been tested scientifically and standardization to ensure efficacy and
safety. Initial stageis screening bioactive compound and then antibacterial
activity assay with paper disc method. Clinical bacterial isolates such as Escherichia
coli and Staphylococcus aureus were used as test organisms. The best treatment
to inhibit the growth of E. Coli and S. aureusis 70% ethanol at a concentration
of extract 1000 mg/ml with inhibition zone respectively 5mm and 6.5mm. Although
in crude extract form, Madurese traditional medicine (herbs) Subur Kandungan
had inhibitory effect on the growth of the E.coli and S.aureus so this
traditional medicine potential as an antibacterial agent. It is recommended
that further work be done to identify the specific secondary metabolite
compound that responsible for this effect, purify it, and standardize as same
as a antibacterial drug.
Keywords: Madurese traditional
medicine (herbs) Subur Kandungan; Antibacterial activity; C. zedoaria; K.
galanga; F. vulgare; and C. asiatica
Penulis: Andik Wijayanto, Romi
Abrori
Kode Jurnal: jpbiologidd150961