PENILAIAN TNF-ALFA PADA HATI MENCIT JANTAN SETELAH PEMBERIAN EKSTRAK ETANOL MANGGIS Garcinia mangostana L DENGAN METODE IMUNOHISTOKIMIA
Abstract: Mangosteen peel
extract is now widely used as an alternative treatment by society as an
anti-oxidant without knowing the side effects. Consumption Monosodium glutamate
(MSG) is used as a flavor enhancer in the food can cause various side effects
due to formation of free radicals in the body such as liver dysfunction. The
research method using true experimental designs aimed at comparing the effect
of ethanol extract of mangosteen peel (EEKM) on liver damage caused by MSG
administration to vitamin E. Of 15 fish samples DDW strain male mice, which
were divided into three treatment groups, namely control group / distilled
water (P0), MSG administration group (P2), group administration MSG and
EEKM(P3). Then assessed liver function as well as evaluating the level of
immunohistochemical staining of liver damage with TNF-α (NBP1-67 821, pAb, 1:50
dilution). Ethanol extract of mangosteen peel and are able to improve the look
of immunohistochemical expression of TNF-α inflammatory process caused by MSG
administration(p>0,05).
Penulis: Nora Maulina
Kode Jurnal: jpkimiadd150617
