UJI BIOAKTIVITAS FRAKSI METANOL DAN ETIL ASETAT TUMBUHAN PAKU SISIK NAGA (DRYMOGLOSSUM PILOSELLOIDES (L) PRESSL.) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS DAN SALMONELLA TYPHI
ABSTRACT: Staphylococcus
aureus is a pathogenic bacterium that causes infection to wound, and Salmonella
typhi is a bacterium that causes typhoid. The dragon scales (Drymoglossum
piloselloides) is one of the plants that can potentially serve as an
antibacterial agent. This research aims to find out the class of compound of
secondary metabolites and the antibacterial activities of methanol and ethyl
acetate fractions of the dragon scales against S. aureus and S. typhi bacteria.
The study was conducted for 3 months with a disc diffusion method (Kirbybauer).
The concentrations of methanol and ethyl acetate fractions of the dragon scales
used in this research were 0,25 g/mL, 0,3 g/mL, 0,35 g/mL, ciprofloxasin 0.005
mg/mL as a positive control and DMSO 10% as a negative control. Research
findings showed that the methanol and ethyl acetate fraction contained
flavonoid and terpenoid compounds. The methanol fraction of the dragon scales
had antibacterial activity against S. aureus bacterium with a strong response
at a concentration of 0.25 g/mL while the ethyl acetate fraction had no
antibacterial activity against S. aureus and S. typhi bacteria.
Penulis: Rian Juni Sumito,
Siti Khotimah, Riza Linda
Kode Jurnal: jpbiologidd160120
