Pengaruh Kadar Raksa Dalam Rambut Terhadap Keparahan Gejala Autisme pada Anak yang Mengalami Gangguan Autistik
Abstract: Autistic
Disorder can happen due to neurological
expressions as the effects of environmental poisons in children who had
genetical deficiency history. Current study found that increasing of mercury (Hg) concentration
in hairs had significant correlation towards increasing of autisme level of severity. Hair analysis may
identify the history of mercury’s exposure in human. This analytical
correlational descriptive study aimed to identify mercury (Hg) concentration in
children with autistic disorder at YAKARI Autism Foundation in Medan and at
State Disability School in Binjai. This study also aimed to analyze the
correlation between the Hg concentration and the symptoms’ level of severity.
Hair samples were taken from 17 children with autistic disorder and 17 normal
children (at similar age and sex). Mercury concentrations were analyzed by
using ICP-OES. CARS were used to examine the autism symptoms’ level of
severity. Majority of autistic disorder subjects (70.6%) had severe autism symptoms. Mean of Hg
concentrations in autism subjects was 1,82 ppm
± 0,52 and in normal subjects was 0,91 ppm ± 0,68. Furthermore, mean of
Hg concentrations in autistic disorder subjects was significantly higher than
in normal subjects (p < 0,05). However, there was no significant difference
on Hg concentrations between mild-fair and fair-severe autistic subjects’ categories. The findings of this
study explain that the severity of autism
symptoms in the autistic disorder subjects do not influenced by Hg
concentrations within their body. Therefore, unidentified factors in this study
might be contribute to the severity of autism symptoms. Future studies related
epigenetics need to be conducted in order to explore another factors contribute
to the severity of autism symptoms.
Penulis: Ellyta Aizar,
Yahwardiah Siregar, Zul Alfian
Kode Jurnal: jpkimiadd150749
