Demographic Characteristic of Fundic Gland Polyp and Its Association with Gastritis in Pathology Anatomy Department, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital
Abstract: Fundic gland polyp
(FGP) is the most common polyp found in the stomach with the incidence of 47%
from all stomach polyps. FGP is more common to be found in female with the
ratio of 5:1 and occurs in the average age of 53-year-old. Gastrin is a hormone
produced by G cell, which function is to facilitate epithelial cell
proliferation. Gastritis is a frequently found digestive tract disturbance.
Torbenson et al showed the presence of chronic gastritis in FGP patients. The
aim of this study is to observe the demographic characteristics of FGP and to
identify the association between number of polyps with morphologic appearances
of gastritis in Anatomical Pathology Department, Faculty of Medicine, Universitas
Indonesia, Cipto Mangunkusumo Hospital in year 2012-2014.
Method: This retrospective study was a descriptive analytical study. This
study was performed by reviewing the slides of FGP cases and evaluating the
severity of gastritis based on visual analog scale from Sydney System (SS).
Results: Study of FGP demographic obtained 44 cases with predominantly
female aged 30 (68.2%), patients’ average age was 55.4 year old with dominant
age group in age group 51-60 year old which accounted for 16 (36.4%). This study was performed in 38 cases. The
frequency of single polyp was 18 and multiple polyp was 20. Most cases were
chronic inflammation which accounted for 21 (55.3%) and mild atrophy 18
(47.4%). Mild intestinal metaplasia was found in 1 case. There was no case of
neutrophil infiltration, H. pylori infection or dysplasia. Chi-square test
revealed that there was no significant association between number of polyps
with gastritis.
Conclusion: Chi-square test which was performed in this study showed there
is no significant association between number of polyps with gastritis.
Keywords: fundic gland polyp
(FGP); gastritis; gastrin
Author: Liza Handayani, Ening
Krisnuhoni
Journal Code: jpkedokterangg170375
