Factors Associated with Surveillance for Early Detection of Hepatocellular Carcinoma in Liver Cirrhosis Patients
Abstract: The minimal number
of hepatocellular carcinoma (HCC) patients diagnosed through surveillance is
proposed as the cause of persistently low number of survival. It is important
to identify the proportion of surveillance for early detection of HCC in
patients with liver cirrhosis and related factors. This study aimed to
determine the proportion of surveillance for early detection of HCC in patients
with liver cirrhosis and related factors.
Method: A cross-sectional study of patients with liver cirrhosis at RSCM
from January to December 2013. The data was obtained from medical records and
confirmed by telephone. Surveillance was required for abdominal ultrasound with
or without AFP at least once a year within 3 years after that period. Factors
studied were gender, ethnicity, education level, income level, availability of
medical insurance, location of residence, surveillance education, cirrhosis
aetiology, and severity of cirrhosis. Then, logistic regression test was used
in the multivariate analysis.
Results: From 200 patients, 50 patients (25,0%) underwent surveillance,
150 patients (75,0%) did not. Bivariate analysis revealed 4 variables with p
< 0.25, gender (p = 0,056), ethnicity (p = 0, 231), surveillance education
(p = 0,005), and severity of cirrhosis (p = 0, 005). Multivariate analysis
showed that the risk factors for surveillance were surveillance education (OR =
2,598; CI 95% (1,325 - 5,094), p = 0,005) and severity of cirrhosis (OR =
1.815; CI 95% = 1,210-2,724; p = 0,004).
Conclusion: Surveillance education and severity of cirrhosis were the
factors associated with surveillance for early detection of HCC in liver
cirrhosis patients.
Keywords: chirrosis of the
liver; surveillance; related factors
Author: Ario Perbowo Putra,
Andri Sanityoso Sulaiman, Juferdy Kurniawan, Kuntjoro Harimurti
Journal Code: jpkedokterangg170371
