Precancerous Lesions in Gastrointestinal Tract
Abstract: Gastrointestinal
cancer is one of the health problems which is frequently found in many people
in the world until now. Studies in gastrointestinal cancer showed early
detection can reduce morbidity and improve the survival of patients. The precancerous
lesions of the gastrointestinal tract are highly potential turn into cancer.
Precancerous lesions can be defined as a change or non-cancerous lesions that
can become cancerous over time.
Precancerous lesions can be found on the entire upper and lower
gastrointestinal tract. Precancerous lesions of the upper digestive tract that
can be found are Barrett's esophagus, chronic gastritis with or without
Helicobacter pylori infection, atrophic gastritis, intestinal metaplasia of the
gastric mucosa, epithelial dysplasia, and adenoma polyp. While precancerous
lesions in the lower gastrointestinal tract are adenoma, inflammatory bowel
disease, chronic infection and hereditary non-polyposis colon lesions.
Precancerous lesions of the stomach in the form of chronic atrophic gastritis,
intestinal metaplasia and dysplasia can be treated with anti-inflammatory and
anti-free radical drugs such as rebamipide and superoxide dysmutase.
Precancerous lesions in the colon in the form of chronic enterocolitis, dysplasia
can be treated with anti-oxidants, anti-inflammatory and anti-free radical such
as anti-oxidants, rebamipide, superoxide dismutase, anti-inflammatory drugs.
Keywords: precancerous
lesions, gastrointestinal tract; intestinal metaplasia; dysplasia
Author: Marcellus Simadibrata,
Randy Adiwinata
Journal Code: jpkedokterangg170387
