Pengaruh suplementasi serat Psyllium husk dan diet rendah kalori seimbang terhadap berat badan, kadar kolesterol high-density lipoprotein, dan trigliserida serum pada obes I
Abstract: The increased
prevalence of obesity will bring a great impact in the health sector, due to
the effect of the influence of organ in the body such as type 2 diabetes
mellitus (T2DM) and cardiovascular disease (CVD). Reduced energy diet and
exercise are effective for management weight loss. During the restriction diet,
an obese person should increase the amount of dietary fiber up to 20−35 g/day,
specifically of soluble fiber, to more effective fat loss and improve serum
high-density lipoprotein (HDL) and triglyceride (TG) cholesterol concentration.
Psyllium husk (PH) is a source of natural soluble fiber obtained from Plantago
ovate Forssk seed.
Objective: The aim of the study have investigated the change of body
weight, serum HDL cholesterol, and TG concentration in obese I after
supplemented PH 8.4 g/day and balanced deficit calories diet (BDCD) for 4
weeks.
Method: The survey used double-blind randomized clinical trial with
parallel design. Subjects were randomly divided into two groups; treatment (T)
group and placebo (P) group. The T subjects received psyllium husk (PH) 8.4
g/day and BDCD 1200 kcal/day and the P subjects received placebo and BDCD 1200
kcal/day. The analyzed used independent t-test and Mann-Whitney.
Results: A total 28 subjects (14 subjects in each group) had completed
the intervention. There were no serious adverse effects reported during the
intervention. Intake of dietary fiber in T group was 17.2 ± 2.8 g/day had
significantly higher than P group 8.6 (5.2−15.2) g/day, although supplemented
with PH didn’t meet the recommendation of fiber intake (20-35 g/day). Decrease
of body weight was -1,8 ± 0,8 kg and triglyceride level was -1,5 (-416−77) in T
group that statistically insignificant difference (p=0,39 and p=0,84) with P
group -1,6 ± 0,9 kg and -10,0 ± 31,3. Soluble supplementation (P group)
increased serum HDL cholesterol concentration was 0,0 ± 4,3 mg/dL that
statistically insignificant difference (p=0,86) with T group -0,4 ± 5,9.
Conclusion: PH supplementation 8.4 g/day and BDCD 1200 kcal/day in obese
I can not reduce body weight, serum high-density lipoprotein cholesterol, and
triglyceride concentration level in 4 weeks.
Keywords: psyllium husk;
balanced deficit calories diet; body weight; high-density lipoprotein cholesterol;
triglyceride; obese I
Penulis: Irnawaty Rasyid
Kode Jurnal: jpkesmasdd140743
