EFEK INTERVENSI BUAH TAKOKAK (Solanum torvum Swartz) TERHADAP KADAR SUPEROKSIDA DISMUTASE ERITROSIT DAN 8-ISOPROSTAN SERUM PADA WANITA DEWASA GEMUK
Abstract: This study aimed to
assess the effect of polyphenols in turkey berry fruits on level of antioxidant
enzyme (erythrocyte superoxide dismutation [SOD]) and oxidative stress marker
(serum 8-isoprostane) in obese adult women. The study was quasi experimental
trial with cross-over design. Eight obese women subjects in Benteng
Village-Ciampea, Bogor District, West Java were randomly assigned to a control
group (n=4), and a turkey berry group (n=4) for 2 x 1 week daily treatment with
a one week wash-out period between treatment periods. Turkey berry group
consumed home diet and ±160 g of cooked turkey berry (as a side dish or snack)
while the control group consumed only home diet. A food record consumption data
was collected twice each week. Blood samples were obtained in the morning at
day 1, 8, 15, and 22 of interventions and analyzed for the level of erythrocyte
SOD and serum 8-isoprostane. The results showed that the different levels of
erythrocyte SOD between post and pre intervention on turkey berry groups was
not significantly different compared to the control group (p=0.607). Whereas,
the different level of serum 8-isoprostane between post and pre intervention on
turkey berry group in which decreasing was significantly different from the
level on control group which was increasing (p<0.05). It seems that daily
consumption of cooked turkey berry fruits can improve oxidative stress
condition.
Keywords: enzyme antioxidant;
oxidative stress; polyphenol
Penulis: Putri Novitasari, Sri
Anna Marliyati, Evy Damayanthi
Kode Jurnal: jpkesmasdd160545
