Pemberian kombinasi probiotik dan zinc terhadap perubahan kadar hemoglobin, albumin, dan indeks massa tubuh pada pasien tuberkulosis paru
Abstract: TB patients are
generally the most productive age group and suffer from chronic energy
deficiency. Therefore, patients with TB requires a combination of chemotherapy
and supplementary feeding as probiotics and zinc to boost the immune response
and nutritional status.
Objective: To analyze the effect of a combined of probiotics and zinc on
the changes of hemoglobin, albumin level, and BMI.
Method: This study is a quasi-experimental, randomized design with pre-post
test control group involving 52 respondents. They were divided into two groups.
The treatment group was given a combination of 1 capsule of probiotics (2
billion probiotics) and zinc 20 mg per day for 28 days. The analysis is paired
t-test, independent t-test, Mann-Whitney, Pearson, Spearman, Covariance.
Results: There was an increase in hemoglobin (p=0.01), albumin (p=0.01)
and BMI (p=0.01). There is no difference between the two groups in the levels
of hemoglobin parameter (p=0.21) and BMI (p=0.12), whereas there is a
difference parameter albumin levels (p=0.01). The effectiveness of
interventions is 4% for hemoglobin levels, 16% to albumin, and 1% for IMT.
Conclusion: Probiotics and zinc for 28 days in patients with pulmonary
tuberculosis may increase levels of hemoglobin, albumin, and BMI, but there is
no significant difference in the changes of BMI. The most powerful influence of
intervention effectiveness is on albumin.
Keywords: albumin; BMI;
hemoglobin; probiotics; pulmonary tuberculosi; zinc
Penulis: Meika Rahmawati
Arifah
Kode Jurnal: jpkesmasdd160598
