Pengaruh ekstrak teh hijau (Camellia sinensis) terhadap kadar malondialdehid (MDA) plasma dan kekuatan genggam tangan lanjut usia
Abstract: Prevalence of
Indonesian elderly has now reached 7%, which is considerably high. Physical
performance is an important health status indicator in elderly. Declining of
physical performance such as hand grip strength in elderly is related to
oxidative stress. Furthermore, oxidative stress plays an important role on the
decreasing of skeletal muscle function. Plasma malondialdehyde (MDA) is a lipid
peroxidation residue that is often used as an oxidative stress biomarker.
Meanwhile, tea is the most widely drunk beverage after water. Green tea
contains antioxidants that can reduce the damages caused by oxidative stress.
Objective: To assess the effect of green tea extract (GTE) on plasma
malondialdehyde level and hand grip strength of elderly.
Method: This was a double-blind experimental with pre-post test and
control group. Fifty-seven elderly people from Balai Pelayanan Social Tresna
Wredha (BPSTW) Abiyoso and Budi Luhur who met inclusion and exclusion criteria
were divided into 2 groups. During 30 days, the first group was given 2
capsules of GTE a day (±168 mg catechin and 95 mg Epigallocatechin gallate
(EGCG) and the second group was given a placebo. MDA was measured by
thiobarbituric acid (TBA)method and hand
grip strength was measured by handgrip hand grip dynamometer.
Results: There was a significant decreasing MDA (p<0,05) in the GTE
group, but not in the placebo group. There was also increasing handgrip
strength in the GTE group but not in the placebo group.
Conclusion: Green tea extract can prevent increasing MDA and declining
physical handgrip strength in elderly.
Keywords: elderly; green tea;
hand grip strength; malondialdehyde; physical performance
Penulis: Fera Nofiartika
Kode Jurnal: jpkesmasdd160591
