Daya Hambat Ekstrak Buah Delima Merah (Punica granatum Linn) Terhadap Pertumbuhan Porphyromonas gingivalis
ABSTRACT: Halitosis is a
common complaint among general population. Porphyromonas gingivalis 33277 is
the most frequent bacteria that cause halitosis. Pomegranate (Punicagranatum
Linn) extract is used to control the number of Porphyromonas gingivalis
population.Bioactive compound of pomegranate is polyphenol (Flavonoids and its
derivate, tanins,ellagitanins) and Alkaloids. Objective : To Analyze the
effectiveness of pomegranate againstInhibition of Porphyromonas gingivalis
Materials and Metdhods :The research used disc diffusion method (Kirby-Bauer)
with 7 treatment group (n=6). Petridish was filled with Agar and inoculated by
Porphyromonas gingivalis. after 5 minutes, set up disk that previously immersed
in100%, 50%, 25%, 12,5%, 6,25% pomegranate extract, distilled water (negative
control) andClorhexidine 0,2% (positive control) on top. The Petridish were
then placed in the desiccator and incubator at 37oC for 24 hours. Zone of
Inhibition were measured using digital caliper by three independent observer
and recorded in millimeter. The result of this study showed that there wereInhibition
zone in all treatment group (except negative control). Results and Conclusions
: Pomegranate extract had antibacterial activity against Porphyromonas
gingivalis at 6,25 minimum inhibitory concentration.
Keywords: Antibacterial
activity, Punica granatum Linn extract, Porphyromonas gingivalis, Kirby-Bauer
disk diffusion method.
Penulis: Alvin Ananda Susetyo,
Sri Hernawati, Dyah Indartin
Kode Jurnal: jpkesmasdd170080
