Daya Hambat Ekstrak Buah Delima Merah (Punica granatum Linn) terhadap Pertumbuhan Staphylococcus aureus
ABSTRACT: Staphylococcus
aureus is the most common microorganism in angular cheilitis. Angular cheilitis
is inflammation in one corner of the mouth or both corners of the mouth may
extend involving the lips commisura and surrounding skin. The prevalence of
angular cheilitis is 0.2-15.1% in children and 0.7-3.8% in adults. One of
alternative treatment by using herbal plants, namely red pomegranate. Red
pomegranate contains flavonoids, tannins, and alkaloids as antibacterial.
Objective: to determine the inhibition of red pomegranate extract on growth of
Staphylococcus aureus. Methods: disk diffusion method with 6 samples in each
study group. The study group consisted of 4 treatment groups (25%, 50%, 75% and
100% red pomegranate extract), positive control group (fusidic acid), and
negative control group (sterile aquades). Data were analyzed using One Way
Anova test and LSD (Least Significant Difference) test. Results and conclusions:
red pomegranate extract has the ability to inhibit the growth of Staphylococcus
aureus. The concentration of red pomegranate extract has the greatest
inhibitory effect on S. aureus growth, that is 75% and 100%.
Keyword: Antibacterial
activity, red pomegranate fruit extract, Staphylococcus aureus, disk diffusion
method
Penulis: Erlita Prestiandari, Sri
Hernawati, Leni Rohma Dewi
Kode Jurnal: jpkesmasdd180037
