EFEK INTERVENSI MINUMAN TEMPE TERHADAP PENURUNAN KADAR LOW DENSITY LIPOPROTEIN
Abstract: The aim of this
study was to analyze the effect of tempe drink intervention on lipid profile of
hypercholesterolemic subjects. This study used a Randomized Controlled Trial
(RCT) design with 51 males and females subjects with the inclusion criterias
were adults aged 25-55 years, not being menopause and pregnant, total
cholesterol levels ≥200 mg/dl and signed informed consent. The subjects were
divided into three treatments - Tempe Drink of A (TDA) formulated from local
sprouted soybean, Tempe Drink of B (TDB) formulated from imported soybean and
control. The tempe drink was given three glasses a day for four weeks,
contained at least 25 g of protein/day. The control treatment was not given the
tempe drink. Lipid profile (total cholesterol, low density lipoprotein (LDL),
high density lipoprotein (HDL) and triglycerides (TG)) was collected before and
after intervention. The results showed
that both TDA and TDB decreased total cholesterol, LDL, and TG of subjects,
respectively 26.7 mg/dl and 17.3 mg/dl; 3.6 mg/dl and 1.0 mg/dl; and 16.2 mg/dl
and 3.7 mg/dl compared to control subjects, but did not increase HDL of
subjects. This implies that tempe drink had beneficial health effect on
lowering total cholesterol, LDL and TG.
Keywords: hypercholesterolemia;
lipid profile; tempe drink
Penulis: Ika Wirya Wirawanti, Hardinsyah,
Dodik Briawan, Made Astawan
Kode Jurnal: jpkesmasdd170510
