EFEK PROPOLIS CAIR Trigona spp. TERHADAP RESPONS IMUN TIKUS Sprague Dawley YANG DIINFEKSI Sthapylococcus aureus
Abstract: This study aimed to
evaluate the effect of liquid propolis of Trigona spp. on the immunological
parameters in mice infected with Sthapylococcus aureus. The effects of propolis
were analyzed using the macrophage activity as determined by the phagocytic
activity and by the production of nitric oxide (NO) in Sprague Dawley rat
peritoneal macrophages and the production of antibodies. The results showed
that the liquid propolis produces (a) an increase in the phagocytic index, (b)
a significant increase in NO production, and (c) an increase over the
production of IgG antibodies. This study indicates that the ethanolic extract
of propolis of Trigona spp. is able to activate macrophages, promote the
production of No and antibodies. The combination of these results suggests that
this extract has an immunomodulatory effect and can boost the immune responsse.
Keywords: antibodies,
immunomodulator; macrophages activity; propolis Trigona spp.
Penulis: Nurbani Kalsum, Ahmad
Sulaeman, Budi Setiawan, I Wayan Teguh Wibawan
Kode Jurnal: jpkesmasdd170512
