Hubungan antara Kadar Feritin dengan Kadar BUN-Kreatinin pada Pasien Talasemia Beta Mayor di RSD dr. Soebandi Jember
ABSTRACT: Major beta
thalassemia patients with iron overload will have increase on ferritin levels.
Free iron can cause damage in several organs including kidney. One of parameter
used to investigate the function of kidney is BUN and creatinine. This study
was aimed to determine the correlation between ferritin levels and
BUN-creatinine levels of major beta thalassemia patients at dr. Soebandi
Hospital Jember. This is an analytical observational study with cross sectional
study design, using 15 patients of thalassemia at the Paediatrics Department of
dr. Soebandi Hospital Jember who met inclusion criteria. The data was obtained
from medical records or patients report book. Data was analyzed with Shapiro
Wilk normality test and Spearman correlation test. The mean of ferritin levels
was 3.145±57,99 ng/mL, BUN levels was 8,87±1,18 mg/dL, and creatinine levels
was 0,53±0,24 mg/dL. The Spearman correlation test for the correlation between
ferritin levels and BUN levels showed r=0,073 and p=0,795 and the correlation
between ferritin levels and creatinine levels resulted r=0,173 and p=0,537. In
conclusion, there was no correlation between ferritin levels and BUN-creatinine
levels of major beta thalassemia patients at the dr. Soebandi hospital Jember.
Keywords: thalassemia,
ferritin, BUN, creatinine
Penulis: Kurnia Elka Vidyarni,
Mohamad Ali Shodikin, Rini Riyanti
Kode Jurnal: jpkesmasdd170105
