The Combination of Probiotic and Calcium Carbonate Decrease Monocyte Count of End-Stage Renal Disease Patient
Abstract: Elevated monocyte
count is correlated to the decrease of renal function and disease progressivity
on end-stage renal disease (ESRD) patients. Probiotic that utilize
lactobacillus species is known to play a role in maintaining imunity system
balance by inducing the monocyte apoptosis. The combination between probiotic
and calcium carbonate could increase probiotic colonization in the
gatrointestinal tract. The aim of this study was to analyze the effect of
probiotic and calcium carbonate combination toward reduction of monocyte count
on ESRD patient at Rumah Sehat Terpadu Dompet Dhuafa Bogor Hospital. This study
was true experimental research with randomized pre-post test control group
design. Twenty four ESRD patient were randomly enrolled into treatment group
(n=12) and control (n=12). The treatment group received probiotic and calcium
carbonate, whereas control group received standardized calcium carbonate for 21
days. There was a significant decrease of monocyte (p=0.03) after
administration of probiotic and calcium carbonate.
Keywords: probiotic, calcium
carbonate, monocyte count, end-stage renal disease
Author: Ari Yulistianingsih,
Mohammad Sulchan, Taufik Maryusman, Shofa Chasani
Journal Code: jpkesmasgg180008
