Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kamboja Putih (Plumeria acuminata) Terhadap Pertumbuhan Streptococcus mutans
ABSTRACT: Most of caries are
caused by Streptococcus mutans. Etanol extract of white frangipani leaf are
supposed to inhibit the growth
of Streptococcus mutans. This extract contains antibacterial
compound such us flavonoid, saponin, tannin, and alkaloid. Purpose : This study
was to determine the antibacterial activity of etanol extract of white
frangipani leaf in variant concentration on growth of Streptocossus mutans.
Method : This study was used well diffusion method with 6 treatment groups.
Each petridish were filled BHI-A and inoculated by S. mutans followed by making
6 wells using the borer (diameter 5 mm) and filled 20 µL of white frangipani
leaf extract 50%, 25%, 12,5%, 6,25%, povidone iodine as positive control, and
aquadest sterile as negative control into the well. Each petridish were
incubated at 37ºC for 24 hours. The inhibitory zones were measured by using
digital calliper. Results: The result showed that there were inhibitory zones
in positive control, extract 50%, and 25% treatment groups and there is no
inhibitory zones in negative control, extract 12,5%, and 6,25%. Conclusion:
Etanol extract of White frangipani leaf has antibacterial activity against the
growth of Streptococcus mutans with minimum inhibitory concentration of 25% .
Keywords: Antibacterial
activity, Streptococcus mutans, Etanol
extract of white frangipani leaf
Penulis: Affian Hudatama Putra,
Yani Corvianindya Rahayu
Kode Jurnal: jpkesmasdd170099
