ANALISIS KINETIKA PELEPASAN TEOFILIN DARI GRANUL MATRIKS KITOSAN
Abstract: Moment the drug
dosage form development, it is important to study the drug release or
dissolution that is recognized as an element in drug development. Mathematical
models could help optimize the design of drugs to produce models of drug
release information. Analysis of quantitative values obtained when depicting
dissolution drug release profiles more easily when the mathematical concepts
used to describe the drug release kinetics model. Model release of drugs known
include zero order, first order, Higuchi models, models Hixon Crowell and
Peppas Korsmeyer models. The purpose of this review apply mathematical concepts
to study the phenomenon of drug release theophylline granules matrix made from
chitosan
Keywords: release, kinetics, theophylline and chitosan
Penulis: Suprianto
Kode Jurnal: jpfarmasidd160444
