Antibacterial Activity From Cucumber (Cucumis sativus .L) Ethanol Extract In Deodorant Roll On Dosage Form
Abstrak: Body odor of human
skin usually occur due to excessive production of sweat glands couples with the
presence of bacteria. The active ingredient to prevent body odor are chemicals
materials from alum or sodium in order to have negative effects such as skin irritation,
Alzheimer disease, prostate and breast cancer. Natural materials technology has
been development as an active agent by using cucumber (Cucumis sativus .L). The
purpose of this research to conduct a deodorant roll on a stable and qualified
physical quality and also develop the use of extract cucumber as an
antibacterial Staphylococcus epidermidis. Cucumber extraction has been done by
maceration with ethanol 70% for 4 days and then divided into three formulation
extract (5%, 10%, and 20% (b/v)). All of the formulations has been tested by
zone inhibition, organoleptic, homogenity, pH, viscosity and irritation test.
The results given that all of the formulations meet the quality requirements of
physical and the best formulation extract 20% able to inhibit bacterial by 26
mm as a largest diameter of the inhibitory zone. In addition the stability of
deodorant roll on form were performed accelerated stability test for 35 days at
room temperature (28°C) and 40°C. The test results indicate that the stability
of the extract 10% quali ed physical quality during storage at room temperature
(28°C) and high temperature (40°C) for 35 days. While in the extract 20% at
high temperature (40oC) physical changes characterized by the deposition.
Keyword: cucumber, deodorant
roll on, antibacterial
Penulis: Laila Susanti, Subur
Widodo, Qurrota Aini, Dyah Rahmawati
Kode Jurnal: jpfarmasidd170596
