Antiinflammatory Activity Patch Ethanol Extract of Leaf Katuk (Sauropus Androgynus L. Merr)


Abstract: The leaf katuk (Sauropus androgynus L. Merr) extract at a dose of 400 mg/kg BW had antiinfl ammatory activity in rat by induction of carrageenan. Patch are adhesive plasters containing medicinal substances placed on the skin to delivery active substances. Patch can off er practicality, comfort and accuracy of dosage in the application of leaf S. androgynus extract.This research was alaboratory experimental research by making patch of leaf S. androgynus extract and infl ammation eff ect used rats as its animal test. Infl ammatory healing activity was seen from the percentage reduction in infl ammation in rats after patch application. Patch of leaf S. androgynus extract dose 400 mg/kg BW has percentage of infl ammatory inhibition ranged between 66,67-100%. Statistical test results usingone-way anova patch leaf S. androgynus extract showed good eff ectiveness in curing infl ammation.Eff ectiveness between leaf S. androgynus extract patch and diclofenac sodium patch relatively the samein curing infl ammation.
Keywords: patch, antiinfl ammatory, leaf S. androgynus extract
Penulis: RISE DESNITA, SRI LULIANA, DESY SISKA ANASTASIA AND MUHAMMAD AKIB YUSWAR
Kode Jurnal: jpfarmasidd180054

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