EFEK ANTIINFLAMASI EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) PADA MENCIT (Mus musculus)
Abstrak: Leaf cherry (Muntingia
Calabura L) empirically been used by the public as an anti-inflammatory drug.
Cherry leaf contains flavonoids are thought to have antioxidant effects. This
study has been tested antiinflammatory effect of ethanol extract of leaves of
cherry (Muntingia Calabura L) in mice (Mus musculus). A total of 15 mice were
divided into 5 groups of 3 animals. Group I (control) are given Na.CMC 1% w/v,
Group II, III, and IV (treatment) were given cherry leaf extract ethanol
concentration of 1% w / v, 3% w / v, and 5% w / v, as well as groups V
(comparison) given Diclofenac Sodium 0.195 mg / 30 gBW. Before treatment all
groups karagen induced with 1% w / v in intraplantar. Antiinflammatory effect
was measured using pleytismometer. The results were analyzed statistically by
one-way ANOVA method. The results showed that the ethanol extract of cherry
leaf has anti-inflammatory effects and the concentration of 3% and 5% w / v has
an effect no different to that diclofenac sodium.
Keywords: Muntingia Calabura
L, antiinflammatory, ethanol extract
Penulis: safriani rahman,
Aulia Wati, Eka Mega Asariningtyas
Kode Jurnal: jpfarmasidd170397
