Efek Antiinflamasi Krim Ekstrak Etanol Daun Kirinyuh (Chromolaena odorata (L) R.M. King & H. Rob) Secara Topikal Dan Penentuan Jumlah Sel Leukosit Pada Mencit Putih Jantan
Abstrak: The research about
the anti-inflammatory effect of ethanol extract of kirinyuh (Chromolaena
odorata (L) R.M. King & H. Rob )that gave topically with granuloma pouch
method. Inflammation was induced by carrageen 2 % in thesesame oil gave in
subcutaneous. Extract administered topically in cream which was given on graded
concentrate: 2,5 %; 5 % and 10 % for 4 days. Diameter of inflammation, volume
of edema, and amount of leukocytes cell in the mice white male were being the
parameter of this research. The parameter which was obtained at the end of the
research was showed that the ethanol extract of kirinyuh(Chromolaena odorata
(L) R.M. King & H. Rob ) in graded concentrate 2,5 %; 5 % and 10 % can
suppress the increase of parameter. They were significant difference between
increasing doses of ethanol extract of kirinyuh(Chromolaena odorata (L) R.M.
King & H. Rob ) with graded dose to diameter of inflammation, volume of
edema, and amount of leucocytes cell in the blood significantly (p<0.05).
Kata Kunci: Chromolaena
odorata (L) R.M. King H. Rob; Anti-inflammatory; leucocyte, Cream
Penulis: Ifora, Helmi Arifin,
Rella Silvia
Kode Jurnal: jpfarmasidd170363
