EFEK EKSTRAK ETANOL DAUN SINGKONG (Manihot Utilissima Pohl) SEBAGAI OBAT ALTERNATIF ANTI REMATIK TERHADAP RASA SAKIT PADA MENCIT
Abstract: Medicinal plants
used for generations one of which is crop cassava leaves. Cassava leaves is
believed to cure rheumatism, gout, anemia, constipation, and to increase
endurance. This study aims to determine the Effects Of Ethanol Leaf Extract
Singkong (Manihot Utilissima Pohl) As Drug Alternatif Antirheumatic Of Pain On
Mice. This study was an experimental study using 25 mice. These animals were
divided into five groups where each group consisted of 5 mice. Cassava leaf
extracts as a control test, flamar gel as a positive control, and distilled
water as a negative control. Observations were made for 45 minutes using a hot
excitatory response in the form of a decrease in a lick or jump after the
treatments. The results showed a decline in the response of mice to lick the
feet or jump to the heat stimuli were administered after administration of
cassava leaf extract. Cassava leaf extract has an effect antirheumatic to pain
in mice. Based on the analysis of SPSS best dose in this study is the first
dose (0.65mg / 20gr mice BB).
Keywords: Cassava leaves,
Antirheumatic, Mice, Pain
Penulis: Setya Enti Rikomah,
Elmitra, Diana Gustina Yunita
Kode Jurnal: jpfarmasidd170153
