EFEK HIPOTENSIF DARI ACEi DAN ARB PADA PASIEN DIABETES MELLITUS DAN HIPERTENSI DI RSUD. ABDUL WAHAB SYAHRANIE SAMARINDA
Abstract: More than two-thirds
of patients with type 2 diabetes also experience hypertension whose development
coincides with hyperglycemia, where each disease has a tendency to influence
the increased risk of other diseases. Sundry new guidelines, such as the
National Joint Committee 8, the American Diabetes Association recommend blood
pressure targets in the diabetic population of <140/90 mmHg to reduce
cardiovascular risk and prevent the progression of nephropathy. This study aims
to determine whether there is a difference in achieving blood pressure target
< 140/90 mmHg according to Join National Committee 8 between ACEi and ARB in
patients with type 2 diabetes with hypertension. This research was conducted
using a retrospective at internist clinic of Abdul Wahab Syahranie hospital, by
taking secondary data from the medical record from blood pressure o 49
outpatients received a single antihypertensive either drug ACEi 29 people or
ARB 34 people. This study showed that the achievement of target blood pressure
by <140/90 mmHg (JNC 8 guideline) between ACEi 7 (28%) and ARB 5 (20,8%)
group and it can be concluded that between ACEi and ARB drugs(P=0.5) there was
no differsignificantly in achievement blood pressure target on type 2 diabetes
with hypertension.
Keywords: ACEi and ARB; DM
type 2; Hypertension; Blood pressure
Penulis: Rusdiati Helmidanora,
Triswanto Sentat
Kode Jurnal: jpfarmasidd170162
