EFFECT OF BLACK RICE BRAN EXTRACT (Black Rice Bran) TO DECREASE DECREASE OF GLUCOSE LEVEL IN DIABETIC RATS
Abstract: Black rice bran is
one of processed foods derived from plants and has a decreasing effect of blood
glucose levels. Major component of anthocyanin in black rice bran that
functions in lowering blood glucose concentration is cyanidin 3-glucoside.
Fifteen male rats Sprague-Dawley strain were selected randomly and divided into
5 groups with the same number in each groups. These groups were consisted of
normal control,negative control, and black rice bran extract treatment with
dose of 50, 100 and 200 mg/kg of bodyweight(b.w.). Each of them were induced to
experience diabetes by alloxan 150 mg/kg of b.w. Measurement of blood glucose
levels was done by using visible spectrophotometer at 546 nm. The samples were
collectedbefore and after alloxan injection, and after 4, 7, and 10 days later
to observe the changes of blood glucoselevels. The results showed that black rice
bran at 200 mg/kg of b.w. was able to lower the glucose levels, which amounted
for 131,33 ± 8,08 mg/dL after 10 days of injection.
Keywords: Black rice bran,
anthocyanin, antidiabetic
Penulis: Novita Sari, Arifah
Sri Wahyuni
Kode Jurnal: jpfarmasidd170435
