EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum) MENURUNKAN KADAR GULA DARAH MENCIT DIABETES
Abstract: Diabetes mellitus is
one of desease that have a large population and trend to increase. sulfonylurea
and biguanide are almost used treatment but have unexpected side effects. The
research still necessary to seek alternative medicine, such as Piper crocatum.This
study aimed to determine the effect of ethanol extract of red betel leaves on
blood sugar levels and body weight of mice (Mus musculus L.) diabetes. This
riset was started to produce simplicia and drilled become powders, continued
extract with 70% ethanol. The extract was evaporated with rotary evaporator
until obtaine crude extract. And then screen it that determine phytochemical.
To continued test on tolerance of level of glucose then mice diabetes induced
aloxan.In summary, extract of red betle ethanolic has contained alkaloid,
quercetin flavonoid, steroid and fenolic compounds and decreased level of
glucose in blood mice diabetes. Besides, it can reduce lose of weight symptom.
Keywords: Piper crocatum, mice
diabetes, aloxan, lose of weight
Penulis: Ambali Azwar Siregar,
Urip Harahap, Mardianto
Kodre Jurnal: jpfarmasidd150518
