FORMULASI DAN EVALUASI KRIM EKSTRAK BAWANG TIWAI (Eleutherine bulbosa)
Abstract: Exposure of the skin
to ultraviolet (UV) radiation from the sun has various adverse effects,
photoaging and skin cancer are of great concern. The ability of botanical
antioxidants for prevention of photocarcinogenesis and photoaging had been
widely known. Bawang tiwai (Eleutherine bubosa) is traditionally used by the
native people of Kalimantan for cancer treatment. The ethanolic extract of
bawang tiwai originated from Banjarbaru district, South Kalimantan had strong
antioxidant activity. The objective of the study was to formulate Eleutherine
bulbosa extract into cream and evaluate its scavenging activity. Antioxidant
activity of Eleutherine bulbosa cream was assessed by
2-diphenyl-1-picrylhydrazyl (DPPH) method. The Eleutherine bulbosa extract was
incorporated into five cream formulas in varied concentration of emulsifying
wax and cetyl alcohol. Evaluation of cream including physical appearance, pH,
viscosity, stability, and microbial growth test. The result showed that
Eleutherine bulbosa cream has antioxidant activity and good physicochemical
quality
Keywords: antioxidant, cream,
bawang tiwai, Eleutherine bulbosa, photoaging
Penulis: Husnul Warnida, Henny
Nurhasnawati
Kode Jurnal: jpfarmasidd170123
