FORMULASI SEDIAAN MOUTHWASH PENCEGAH PLAK GIGI EKSTRAK BIJI KAKAO (Theobroma cacao L) DAN UJI EFEKTIVITAS PADA BAKTERI Streptococcus mutans
Abstract: Research on the
formulation of preparations mouthwash prevention of dental plaque extract of
cocoa beans also has been tested in Streptococcus mutans bacteria by variations
in the concentration of glycerin as a humectant in preparation which aims to
determine the effect of different concentrations of glycerin as a humectant to
the physical properties, chemical properties and inhibition zone Streptococcus
mutans bacteria in mouthwash formula and to know the mouthwash formula that has
the physical quality and the highest antibacterial activity. The method used
includes the step of extraction of cocoa beans, preparation of a mouthwash with
4 formula using variations of glycerin F1 (0%), F2 (15%), F3 (20%) and F4 (25%)
followed by an evaluation formula that includes organoleptic tests, pH test and
the test of inhibition diameter. Tests performed on days 0, 7, 14 and 21. The
results showed the concentration of glycerin as a humectant in a mouthwash
formula cocoa seed extract has an effect on the diameter of inhibition zone,
but did not have a significant effect on the physical and chemical properties
of cocoa seed extracts mouthwash, The concentration of glycerin which meets the
physical quality and the most excellent antibacterial activity that is 15%
contained in the formula 2.
Keywords: Mouthwash; cocoa
beans extract; Streptococcus mutans; glycerin
Penulis: Apriyanti Anastasia, Yuliet,
Muhamad Rinaldhi Tandah
Kode Jurnal: jpfarmasidd170564