FORMULASI SEDIAAN SALEP EKSTRAK ETANOL DAUN ALPUKAT (Persea americana Mill.) SEBAGAI ANTIACNE
Abstract: Currently, the
development of acne drugs (antiacne) use
many natural materials because the natural materials can minimize the
side effect if compared with synthetic chemicals drugs. Acne can caused by
propionibacterium acnes, staphylococcus epidermis and staphylococcus aureu. One
of plants that can be used for acne treatment is leaves of Avocado (Persea
americana Mill). The aim of this study was to know whether the ethanol extract
of leaves of avocado (Persea americana Mill.) can be made into an ointment preparations
that fulfill the requirements. Sample in this research was extract of avocado
leaves which used maceration method. The ointment formulations were made into
some variation concentrations of PEG 400 and PEG 4000: Formula I (30%:70%);
Formula II (50%:50%) and Formula III (70%:30%). The results show that the
ointment of avocado leaves which fulfilled the requirements of physical
properties is formula III with concentration of PEG 400 70 % and PEG 4000 30 %
Keywords: Persea Americana.
Mill., Anti-Acne, Physical Stability Ointment
Penulis: Yulistia Budianti
Soemarie, Tri Astuti, Nur Rochmah
Kode Jurnal: jpfarmasidd160470
