FORMULASI SIRUP EKSTRAK DAUN SENDOK (Plantago mayor L.) SEBAGAI EKSPEKTORAN DENGAN PARAMETER UJI MUKOLITIK
Abstrak: Traditional medicines
that derive from the plants processed in the form of traditional herb have
provided a lot of contribution to the maintenance the health of community.
Greater plantain (Plantago mayor L.) is one of natural materials that is useful
as expectorant, however, so far the use is still processed traditionally by
community. To find out and make sure that the ethanol extract of greater
plantain (Plantago mayor L.) can be formulated to be syrup expectorant, then to
determine the most effective concentration in lowering the viscosity of fluid
mucus of every formula made. In this research, the syrup ethanol extract of
greater plantain (Plantago mayor L.) was made with concentration variation of
6%, 8%, and 10%. Observation was made by looking at the lowering of viscosity
of fluid mucus that has been diluted with phosphate buffer pH 7 by using
viscometer Ostwald through the flow time. Based on the test result ANSIRA to 3
formulas of syrup expectorant and negative control, it was proved that the
concentration of ethanol extract of greater plantain (Plantago mayor L.) in the
treatment of this research significant effected in lowering the viscosity of
mucus with price F count > F table or 66, 3181 > 4, 07 on the test level
of 5% and 66, 3181 > 7, 59 on the test level of 1%. With the price KK 4, 11%
then further test was done using BNJ test. Based on the test result BNJ, it was
known the formula of syrup expectorant that most effective is the formula II
with the concentration of ethanol extract of greater plantain 8%.
Keyword: Greater plantain,
Syrup Expectorant, Mucolytic Test, and Viscosity.
Penulis: Lutfiana Kusuma Wati
Kode Jurnal: jpfarmasidd170395
