Health-Related Quality of Life of Type 2 Diabetes Mellitus Outpatients at Dr. Sardjito Hospital, Yogyakarta, Indonesia: An Insulin-Based Therapy Approach
Abstract: Diabetes mellitus
type 2 is a lifelong disease which needs an intensive therapy to maintain stable
blood sugar levels. Insulin has been proven as an effective treatment modality
for type 2 diabetes mellitus patient. The main aim of this research was to
evaluate the effect of insulin based therapy (insulin monotherapy-combination
therapy of insulin with oral hypoglycemic agents) towards the health related
quality of life in type 2 diabetes mellitus outpatient at Dr. Sardjito
Hospital, Yogyakarta. This study is a descriptive cross-sectional study design
without control. The methods of collecting data includes conducting
questionnaires, interviews and examining medical records of patient. Data were
taken concurrently from patients who visited Endocrinology Clinic of Dr.
Sardjito Hospital from July 2012 until April 2013. Inclusion criteria for the
participant were as follows: participant was a type 2 diabetes mellitus
outpatient with insulin based therapy, had no languange barrier and was able to
participate the study. Participants were excluded in this study if they had a
mental and language retardation, uncomplete medical records, and was a pregnant
woman. The quality of life was measured by Diabetes Quality of Life Clinical
Trial Quessionnaire (DQLCTQ). The statistical analysis used in this study was
Mann‑Whitney for QoL analysis based on the type of therapy (insulin
monotherapy and combination therapy of insulin-oral hypoglycemic agents). The
results from 137 patients shown that patients who received combination therapy
had the largest percentage (73%) while the smallest percentage (27%) were
single therapy. Whereas, the type of therapy (insulin monotherapy-combination
therapy of insulin with oral hypoglycemic agent) significantly influenced the
energy domain (p=0,027).
Keywords: Health related
quality of life, insulin based therapy, type 2 diabetes mellitus
Penulis: Lolita, Tri M.
Andayani
Kode Jurnal: jpfarmasidd170004